Coronavirus Disease 2019 (COVID-19) and late Pregnancy Loss in Infected Pregnant Women: A Mini Review

Document Type : Systematic Review


1 Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

3 Department of Medical Genetics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

4 Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

5 Department of Medical Laboratory Sciences, School of Paramedical Science, Shiraz University of Medical Sciences, Shiraz, Iran

6 Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran


Background: One of the main issues for health care systems during the coronavirus disease 2019 (COVID‑19) was whether infected pregnant women would have pregnancy complications compared with healthy pregnant women during the pandemic. There was no sufficient data about the risk and rate of late pregnancy loss in pregnant women infected with COVID-19. In this study we reviewed the late pregnancy loss in infected pregnant women with COVID-19.
Methods: A comprehensive bibliographic search was conducted in PubMed, Google Scholar, SciELO, Springer Link, China National Knowledge Infrastructure (CNKI) platforms, and Wan Fang database to identify relevant studies published up to September 10, 2020.
Results: A total of seven cohort studies exclusively on late pregnancy loss and infected women with COVID-19 were included.
Conclusion: No evidence supported higher risk of late pregnancy loss in pregnant women with COVID-19. We suggested that the pandemic rapidly unfolds, it is critical that medical health care staffs keep up to date and caution should be undertaken to further study and monitor possible infection in the late pregnant mothers.


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